Excerpt: "Inevitably, someone who hasn’t seen me for a while will remark that I’ve lost weight, but people are much likelier to notice that I’m tall — as if somehow they’d missed that before. If you’re tall and fat, you look like you’re in proportion. Once you’re tall and (relatively) skinny, it becomes obvious you’re all arms and legs. I’m back to what I last weighed as a teenager, and some of that sense of awkward gangliness has returned...."
October 8, 2025
"I’ve lost 4 stone on Wegovy. Now I look like a weedy nerd."
Good headline... for a piece in the London Times by James Ball.
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22 comments:
How much is a stone?
Stripes.
In 20 years the pancreatic and liver disease class-actions on GLP-1 agonists is going to be epic.
A stone is 14 pounds. It sounds as though it might be too good to be true.
Tall people are supposed to be skinny. Otherwise natural selection and flying coach would have filtered them out of the gene pool long ago.
Wegovy and glp1/ozempic are peptides that you can make yourself with amino acid sequencers. People have been making them for a long time.
The drug companies are trying to make it illegal so you have to buy their brand name crap.
RideSpaceMountain said...
In 20 years the pancreatic and liver disease class-actions on GLP-1 agonists is going to be epic.
Most of these compounds are amino acid chains your body already produces and uses to signal every day body functions.
We have learned more about how the body actually works in the last 10 years than previous history. Most peptides are sold as research use only. It is only recently that the giant drug companies have tried to make it illegal to make yourself and multiply the price.
I’ve lost 25 pounds in the last 4 months. No drugs, basically a modified carnivore/keto diet. I count carbs, calories not so much. When I go shopping for groceries I really notice how many carbs the stores are pushing on us. The number of fat people I see shopping far outweigh the number of skinny people and their carts are filled with carbs in all its various forms. Sometimes I think the nefarious they are trying to kill us.
This is why most Joe Bro influencers recommend weight lifting during significant weight loss. FYI, 4-stone equals approximately 1/3-boulder
Wegovy and glp1/ozempic are peptides that you can make yourself with amino acid sequencers. People have been making them for a long time.
Does everybody know what amino acid sequencers are or do we have to go to Reddit to look this up?
David53 said...
I’ve lost 25 pounds in the last 4 months. No drugs, basically a modified carnivore/keto diet. I count carbs, calories not so much. When I go shopping for groceries I really notice how many carbs the stores are pushing on us. The number of fat people I see shopping far outweigh the number of skinny people and their carts are filled with carbs in all its various forms. Sometimes I think the nefarious they are trying to kill us.
Our bodies were made to be in ketosis. We naturally get our energy from protein and fat.
No animal in the world preferentially subsists on processed carbs. They are not a thing. They just produce a fat human. Any animal you feed carbs will become fat and unhealthy.
Well over 90% of the shit in supermarkets is poison.
Randomizer said...
Wegovy and glp1/ozempic are peptides that you can make yourself with amino acid sequencers. People have been making them for a long time.
Does everybody know what amino acid sequencers are or do we have to go to Reddit to look this up?
Don’t use Reddit. Use grok or Gemini or one of the other llms. I am at work or I would give you more.
@david53 I did the same thing, basically cut out carbs and did intermittent fasting, and I dropped 13 pounds in 6 weeks and I wasn't overweight. Feels amazing. Now I just maintain. Keto diets have this ability to really make you feel full for a long time. Now if I could just cut out the alcohol!
That's complete b******* Achilles. Humans are made to run on glucose. Trying to run on fat and ketones is extremely energy intensive and extremely inefficient. But go ahead keep putting diesel fuel in your gasoline engine.
I shed about that much (as mentioned on my profile) after I retired in 2015 simply by eating less, but healthier, food.
The transformation was such that people I hadn't seen in a long time asked if I had been sick.
Since about 2022 though, I've gained about half of it back- a combination of things have reduced my exercise substantially.
I'm on too many pharmaceuticals as it is, and have no desire to try these new drugs.
looked 45, looks 38
A tall man the size of a skinny man.
A few years ago, I lost 90 pounds through a combination of intermittent fasting and calorie control. Once I stopped closely tracking what I was eating, though, the weight started to creep back. When I told my new physician that I had lost that weight without any drugs, she replied, "That's impressive." Now I'm determined to get back to a healthy weight and prove that I can lose the weight and keep it off. In the past 10 weeks, I've lost 20 pounds. My rate of loss is slowing a bit, but I know that consistency will pay off.
I've maintained my motivation with the use of the Happy Scale app. I love tracking my weight and seeing the predicted dates for hitting certain milestones.
News for you, Jimmy--you looked like a fat nerd previously. Skinny is better.
Over the past five months I’ve reshaped my lifestyle through clean eating and consistent training — four days of lifting and three days of cardio. I started around 260 lbs (peaking at 266 after a creatine load) and I’m now down to 225 — over 35 lbs lost while getting stronger every week. A1c and liver enzymes are normal, cholesterol and triglycerides have fallen through the floor, and my energy, mood, and focus are all way up. My projections have me hitting my body-fat target by February.
These days I’m repping squat, chest press, and deadlift at or above my body weight, the leg press is closing in on 3× body weight, and the squat machine’s almost 2×.
My wife and I — both around 50 — have been doing this together, and this has been the way for us. We got lucky and found a good gym with community. At the end of the day, it is discipline and making the change for yourself. You have to make it a priority.
Howard said...
That's complete b******* Achilles. Humans are made to run on glucose. Trying to run on fat and ketones is extremely energy intensive and extremely inefficient. But go ahead keep putting diesel fuel in your gasoline engine.
Your liver makes glucose when operating properly. You have about 5grams of sugar in your blood at most times mostly for your brain which only runs on glucose.
If you go much above 5 grams of sugar in your blood your body produces insulin and it goes into emergency procedures to lower your blood sugar. Your liver can store a bit of sugar but if you are constantly eating carbs you will get fatty liver among other things.
Your liver will convert several things to glucose but it prefers protein and fat. Your blood sugar remains very constant when you eat low/no carb diets because that is what your liver is meant to do.
When you eat carbs there are massive spikes in blood sugar that are very much like massive spikes in blood alcohol. You are quite literally poisoning your liver with carbs in the same way you poison it with alcohol. You get fatty liver disease and you get insulin resistance and higher inflammation levels and all sorts of things that are not good.
There is a reason why everyone who switches to keto\carnivore diets feel better after a week or two.
As a previous marathon competitor(16 including 4 Bostons after 50) I found out early what hitting the WALL really meant Most can store up to around 20 miles worth of glycogen before your body depleted therefore the "wall" syndrome. I learned early on to keep a small roll of glucose tabs on my competitions and in all 16 marathons I only crashed once.The body runs on glucose is correct.(glycogen is the storage compartment) In my last Boston(2004 86degrees on the course) I was depleting early because of temps.20700+ runners started that race and 3600 didnt finish and I believe it was around 150+ actually taken off course to the hospital.You could hear the ambulances during the whole race, not paying attention to heat and distance.In 2000 it was around 50+ and cloudy perfect.2001 53 good,2003 70 little warm and 2004 brutal 86 at finish.Talk about glycogen depletion on the two above 6o days.Weather ,pace ,weight all play factors in depletion.My slowest run in 2004 but my most accomplished having learned about pace heat storage etc.3: in 2004 other 3 races under 3:30(qualified in 3:17 at 53)3:25 WAS QUALIFYING TIME IN ORDER TO RUN IN THE RACE,LATER CHANGED TIME BACK to 3:20 for 50-54 group.(7:30 pace for qualifying Boston race was the cream no need for PR'S hard work qualifying was done
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