७ नोव्हेंबर, २०२३
"Problems arise if the drug slows down the stomach too much or blocks the intestines...."
"While the medications helped Webster slim down quickly.... Webster’s husband allegedly found her unconscious with a brown liquid seeping out of her mouth.... 'It was just pouring out.... If I knew that could happen, she wouldn’t have been taking it.... I never thought you could die from it.'... [T]he manufacturer of Ozempic, Novo Nordisk, said ileus [intestinal blockage] was only reported after its 'post-marketing setting,' suggesting the drugmaker only became aware of the problem after the drug was released...."
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Pharmaceuticals (e.g. vaccines).
There is no magic trick to weight loss. You have to burn more calories than you take in. However you do it. That's it.
This is a tragic story. Diet pills always seem to cause problems.
I lost 30 lbs last winter. Cut bread, pasta, sugar. Still pounded truckloads of Miller Lite and Marlboros. Pretty much chug a protein shake and vitamins in the morning. Eat a big protein lunch. Bring my lunch so what I eat isn't fast food or processed.
Miller Lite and Marlboros for dinner. Kept the weight off for 10 months now.
I really do think it is the processed fast food that makes American's overweight.
" If I knew that could happen, she wouldn’t have been taking it.... I never thought you could die from it"
The same thing fools say about chiropractic treatments - and women taking yoga classes. This is the NewAge and the level of skepticism out there is now practically zero. " I never thought you could die from it" means this guy didn't read very much, because I surely knew it - and a lot more shit women faddishly glom onto - can kill. How? Why?
Because I'm interested in more than the press release.
I won't say I'm a anti Big Pharma guy. But problems like this I think are more linked to the "I Heckin' Love Science!" crowd, which uncritically and without any reasonable levels of skepticism accept scientific pronouncements in the media. These are the same people who assumed there was no risk in taking the Covid vaccine, or there is no cost or downside to switching to a green economy.
Remind me again what the FDA is supposed to be doing.
Safe and effective, for most people. YMMV. Do your homework, and no mandates. And don't take the whole bottle in one dose. It's 2023, not 1973, and we are fatter now.
Disclosure: long LLY, 800 shares. Inherited, with a basis of less than $5. LLY makes Mounjaro, the soon-to-be blockbuster rival to Novo Nordisk's Wegovy, and works in a different way, but the warnings apply to all drugs in the weight loss category.
So was it seeping or pouring? Cause I could handle a little seepage, that's no big deal, but nobody wants something pouring out of their mouth. Pouring's a deal breaker.
...And here I thought that all the risks of these drugs were covered on TV in the 30-second spot ads. Smiling people looking awesome while the voice-over goes at 1000 words/minute about exotic this or that side effect.
Maybe that indigestible chunk of "disclosure" gets stuck in the listener's intellectual passage? Blocking both comprehension and the ability to make intelligent decisions?
Seems like she thought Ozempic just caused weight to be lost rather than how it does. If you continue to eat at the same levels, not only will you not lose weight, you’ll increase the chances of acid reflux, which can also cause you to aspirate on what is essentially vomit. You can just vomit, but if you try to sleep when this is occurring, you might have issues. Better to take the clues the meds give you to slow down consumption, which will also help you lose that weight without the feeling of hunger.
These drugs weren't developed as weight loss drugs- they were developed to treat diabetes, and they were approved as treatments for diabetes.
I predicted last year that these drugs would end up having unforeseen deleterious effects if their use as a weight loss drugs grew. Their benefit probably still outweighs the bad side effects (note" I am not taking into account the monetary costs involved in paying for them), but they will be misused just like the Fen/Phen drugs were misused.
Quick fixes with collateral damage is a popular theme.
O,O,O Ozempic. I guess it's not magic after all.
Until these drugs became popular for weight loss, the body positivity folks tried to sell the concept that being obese was not a matter of eating too much. Rather, a person had a natural weight that no amount of will power or exercise could change; there might be temporary discrepancies between actual weight and normal, but there was an inexorable trend to whatever a person was "supposed" to weigh.
Now, with drugs that actually decrease appetite (by interfering with normal GI function) and subsequently decrease calorie intake, obesity is a disease that is cured by medication. Unfortunately, for more than a few people like the woman described here, the cure is much worse than the disease.
Just a matter of time before the lawyers put Ozempic et el. off the market and we're back to what Dr. Bill Burr recommends for weight loss: "Eat a salad!"
Seems like the only fad drug or treatment of recent years that hasn't caused deaths or severe harm is Ivermectin. And we all know what the feds and pharmaceutical companies did to quash any promotion of it.
I am taking Ozempic for my type 2 for nearly 2 years.
I did loose 10 pounds, but I am NOT eating as I should; AT ALL.
I hope I can take this story as a wake up call, and start to
reign in my eating. At $1000 per month (I pay 5 bucks)
this stuff is way too expensive to waste.
“Seems like she thought Ozempic just caused weight to be lost rather than how it does. If you continue to eat at the same levels, not only will you not lose weight, you’ll increase the chances of acid reflux, which can also cause you to aspirate on what is essentially vomit. You can just vomit, but if you try to sleep when this is occurring, you might have issues. Better to take the clues the meds give you to slow down consumption, which will also help you lose that weight without the feeling of hunger.”
“These drugs weren't developed as weight loss drugs- they were developed to treat diabetes, and they were approved as treatments for diabetes.”
And it seems to work just fine. Talked my GP into switching me from Levimir (time release insulin) to Ozempic last spring. Started at the lowest dosage. Then they tried to up it. But it works so well (A1C of 6.1) that I refused. Lost about 20 lbs, through a combination of appetite suppression and higher metabolism. On Levimir and Meformin, I struggled to stay around an A1C of 7. For me, Ozempic. Has been a miracle drug. Another 10 lbs, and I will be back to my weight at about 25.
Luckily, as a long term diabetic, my health insurance pays for most of the drug. I have heard of it selling for $1200 or so. I have been paying a bit over $100 every couple months - less than I was paying for Levimir.
this has been showing up in my browser hopefully not like this
It takes awhile of not pooping for it to lead to fecal vomiting. Know the side effects of what you take. Notice when you aren't well. Do something about it.
Not indicated for weight loss. Wonder if she was paying out of pocket because most insurance companies won’t pay unless it’s for diabetes.
One way to lose weight is to eat smaller portions than the norm. Portions these days are huge; I got three sandwiches out of my last Subway sandwich. But anyhow you can eat all your favorite foods, just eat a half-size portion at first. Kill your hunger, then stop eating. Don't heap up your plate and clear it.
I take Omeprazole for GERD. You're not supposed to take it long-term - apparently it increases "risk of death from all causes," I assume by changes the chemistry of the stomach (it's a proton pump inhibitor so it reduces acid production, which, you know, exists for a reason). I know this; I lost more than the recommended weight and still suffered the GERD, so I still take it.
There are other measures I can take - dietary changes that I am loath to make (all the things I like the most are the things that tend to trigger GERD, dang it). I am at least trying to change the timing of my evening meal, and I can try to walk down my dosage...
Basically, I have been given something to think about.
Overnight. America went from Victoria's Secret promoting lingerie on fat women to a complete reversal and now back to skinny smokin' hot models.
Now we have another dangerous quick weight loss drug on the market. This poor woman will not be the first victim of the reversal. Now, we will over-correct just like Americans do.
Exercise and eating less. I was diagnosed with diabetes two years ago. Because of it I’d already lost 50 pounds. Since then I’ve lost 50 more. I walk between 15-20,000 steps a day. It’s over a two hour time commitment , but if you stay with it you get healthier. I have not taken Ozempic or Wegovy and I am glad for it.
Jamie-
You probably already know this, but there are several recently developed effective procedures for GERD that may allow you to get off the PPI. Some can be done with endoscopy and require no incisions, others are scope surgeries that require at most a night observation in hospital. You are right to be concerned about taking omeprazole indefinitely.
With success and the upcoming wedding, likely overdid it.
Gonna be a helluva wedding celebration.
The cancer diet is effective, though I don't recommend it.
She took two, overlapping meds. Might even have dosed beyond the label. And it made her sick. Did she stop? Did she consult her doctor? Did her Doctor prescribe/know about her use of both drugs?
No matter. She just HAD to wear a size smaller dress.
Death by vanity.
It is bad the side effects were not listed. But I doubt the label will now say don't use these double up combos.
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